Volumetric Mesh Parameterization to a Canonical Template

Abstract

We present a volumetric mesh-based algorithm for mapping the placenta to a canonical template to enable effective visualization of local anatomy and function. Monitoring placental function in vivo promises to support pregnancy assessment and to improve care outcomes. We aim to alleviate visualization and interpretation challenges presented by the shape of the placenta when it is attached to the curved uterine wall. We flatten a volumetric mesh that captures placental shape to resemble the well-studied ex vivo shape. We formulate our method as finding a piecewise affine map from the in vivo shape to an ellipsoidal or a cylindrical template while minimizing the symmetric Dirichlet energy to control distortion throughout the volume. Local injectivity is enforced via constrained line search during gradient descent. We evaluate the proposed method in the context of a twin pregnancy study that includes MRI scans of seven women. We achieve sub-voxel accuracy in mapping the boundary of the placenta to the template, while successfully controlling distortion. We demonstrate that our approach enhances visualization of the placental anatomy and is generalizable to map to a number of canonical templates.

Publication
Massachusetts Institute of Technology SM Thesis