Department of Mathematics

18.418: Topics in Computational Molecular Biology

Covers current research topics in computational molecular biology. Recent research papers presented from leading conferences such as the International Conference on Computational Molecular Biology (RECOMB), the Pacific Symposium on Biocomputing (PSB), and the Intelligent Systems for Molecular Biology (ISMB). Topic areas include original research (both theoretical and experimental) in genomics, molecular sequence analysis, recognition of genes and regulatory elements, molecular evolution, protein, and RNA structure, and combinatorial libraries for drug design. Recent research by course participants also covered.


Attendance is mandatory and it will be taken at each meeting and count toward your overall grade. Participation will also factor into your grade.

The class meeting on Wednesdays will be guest lecturers who will present various research topics. Information concerning the series can be found at the seminar's web page:

The class meeting on Mondays will be either group or individual (depending upon enrollment) projects by student seminar members. A copy of the powerpoint presentation or your notes (typed preferred) with bibliography will be due the day of your talk.

There is not a final for this class.

The class will not meet the following days: Feb 18, Mar 25, Mar 27, and May 20.

Prerequisites: 18.417, 6.085, 6.8745 or permission of instructor.

Please note that only graduate students may repeat the class for credit; undergrads (Juniors and Seniors) are welcomed to take the class once for credit & encouraged to sit in as listeners if they wish to repeat the class. Freshmen and Sophmores are welcome as listeners only & only with permission of the instructor.

Please note that this page and the information on it are subject to change.

Time & Location

Class Meeting Time: 11:30 - 1:00 in The Theory of Computation Lab Room Building 32, Room G575

Office Hours for Professor Berger: 10:30-11:30am, Wednesdays (CSAIL office, 32G-574) or by appointment.


Date Lecture
Feb  6 Bonnie Berger Lecture: Introduction to the Course
Feb 11 Class Discussion Student Presentations
Feb 13 Guest Lecturer Tamer Kahveci
Feb 18 President's Day  No Meeting
Feb 19 Class Discussion Student Presentations
Feb 20 Guest Lecturer TBA
Feb 27 Guest Lecturer Peter Clote, BU
Mar  4 Class Discussion Student Presentations
Mar  6 Guest Lecturer TBA
Mar 11 Class Discussion Student Presentations
Mar 13 Guest Lecturer TBA
Mar 18 Class Discussion Student Presentations
Mar 20 Guest Lecturer TBA
Mar 25  Spring Break No Meeting
Mar 27 Spring Break No Meeting
Apr   1  Class Discussion Student Presentations
Apr   3 Guest Lecturer TBA
Apr   8 Class Discussion Student Presentations
Apr 10 Guest Lecturer Cristian Tomasetti
Apr 15 Holiday (Patriots Day) No Meeting
Apr 17 Guest Lecturer TBA
Apr 22 Class Discussion Student Presentations
Apr 24 Guest Lecturer TBA
Apr 29  Class Discussion Student Presentations
May  1 Guest Lecturer TBA
May  Class Discussion Student Presentations
May  8 Guest Lecturer TBA
May 13 Class Discussion Student Presentations
May 15 Guest Lecturer Sohini Ramachandran
May 20 Final Exams No Meeting

Instructor: Bonnie Berger, Assistant: Patrice Macaluso
Contact Information: bab at mit dot edu, x3-1827, 32-G574, 2-373.
Contact Information: macaluso at mit dot edu, x3-3037, 32-G568.

Please contact Professor Berger via email directly for further information concerning this class.

Site last updated 2 February, 2013 16:48

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