The human brain can distinguish between different categories of sound. For example,
the sound of a human voice and the sound of cutting a carrot are processed much differently in the brain. But
how does the brain make this distinction, and are different brain regions recruited for different categories?
Listening to sounds, an everyday task that mostly occurs subconsciously, is quite a complex
process in the brain. fMRI-MEG fusion allows us to visualize the propagation of sounds at high spatial and
When looking at an image, the visual system employs a
hierarchical processing structure that first identifies the low-level features, such as lines
and edges, then builds on that until the image's representation is complete. fMRI-MEG fusion gives
us an exciting glimpse into the spatial and temporal dynamics of this visual system.
My team and I from Boston University's Neuronal Dynamics Lab
under Professor John White successfully manipulated a mouse's memory. First, we induced a fearful memory in mice by shocking its foot in Context A.
The mouse was then placed in a novel context, Context B. By stimulating the mouse's hippocampus in real time
at the peak of its theta waves, we were able to artificially make the mouse recall the prior fearful memory (shown by freezing) in
Context B. This work won the Outstanding Senior Design Project in Biomedical Engineering award.