Costis Daskalakis The Challenge of High-Dimensional Statistical Hypothesis Testing Abstract: How many samples are necessary to distinguish whether a multi-dimensional distribution is a product measure or 10%-far from being a product measure in total variation distance? As it turns out, answering this question rigorously requires exponentially many samples in the dimension. Similar lower bounds apply to a host of statistical hypothesis testing problems in high dimensions. So what do we really know about high-dimensional distributions and the important phenomena that they model? E.g. what do we really understand about behavior in a social network, or the output of a Generative Adversarial Network (GAN)? I will survey recent work on hypothesis testing for distributions with large support, discuss the challenges arising in high-dimensional settings, and identify research directions towards overcoming these challenges.