Peng Yu,    Ph.D.  2008 Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology Medical Vision Group Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge, MA, 02139 FreeSurfer Group Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown, MA, 02149 Email: pengyu [at] csail [dot] mit [dot] edu Research Publications Teaching Media CV Misc

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Research

I have participated in a variety of research projects on statistical analysis of brain structures and computer-aided diagnosis based on magnetic resonance images in the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital. I work with Bruce Fischl (thesis advisor), Polina Golland and Bruce Rosen. The goal of my thesis work is to develop an automated procedure for detecting and modeling morphological changes of neuroanatomical structures associated with neurodevelopment and various neurological diseases for accurate diagnosis and proper treatments. To this end, I have developed and applied techniques in different areas, including medical image analysis, computer vision, and statistical machine learning, to solve problems in medical image analysis applications. Please see details in my CV.

Publications

H.D. Rosasa, S.Y. Leea, A.C. Bendera, A.K. Zaletaa, M. Vangelc, P. Yu, et al, Altered white matter microstructure in the corpus callosum in Huntington's disease: Implications for cortical "disconnection", Neuroimage, 49(4):2995-3004, 2010.
M.I. Miller, C.E. Priebe, A. Qiu, B. Fischl, A. Kolasny, T. Brown, Y. Park, J.T. Ratnanather, E. Busa, J. Jovicich, P. Yu, B.C. Dickerson, R.L. Buckner, Morphometry BIRN,Collaborative computational anatomy: an MRI morphometry study of the human brain via diffeomorphic metric mapping, Human Brain Mapping, 30(7):2132-2141, 2009.
B.T.T. Yeo, P. Yu, P.E. Grant, B. Fischl1, P. Golland, Shape Analysis with Overcomplete Spherical Wavelets, Medical Image Computing and Computer-Assisted Intervention (MICCAI 2008), Lecture Notes in Computer Science, Volume 5241:468-476, 2008.
P. Yu, B.T.T. Yeo, P.E. Grant, B. Fischl, P. Golland, Cortical Folding Development Study Based On Over-complete Spherical Wavelets, Proceedings of the IEEE 11th International Conference on Computer Vision, Issue 14-21: 1-8, 2007.
P. Yu, et al., Cortical Surface Shape Analysis Based on Spherical Wavelets, IEEE Transaction on Medical Imaging, 26(4):582-598, 2007 PDF
P. Yu, X. Han, F. Segonne, A. K. Liu, R. A. Poldrack, P. Golland, and B. Fischl, Shape-based Discrimination and Classification of Cortical surface. Proceedings of the 18th International Conference on Pattern Recognition, Volume 3: 445-448, 2006.PDF
P. Yu, X. Han, F. Segonne, R. L. Buckner, R. Pienaar, P. Golland, P. E. Grant and B. Fischl, Cortical Surface Shape Analysis Based on Spherical Wavelet Transformation. Conference on Computer Vision and Pattern Recognition Workshop (CVPRW '06), Issue 17-21: 60-67, 2006. PDF
P. Yu, F. Segonne, X. Han, B. Fischl, Shape Analysis of Neuroanatomical Structures Based on Spherical Wavelets. Neuroimage, Volume 26, Suppl 1, Page S47, Organization for Human Brain Mapping Annual Meeting, 2005. 
P. Yu, D.H. Salat, P. Golland, D. S. Tuch, H. D. Rosas, B. Fischl, Subdividing the Corpus Callosum Based on Morphometry and Diffusion Anisotropy. International Society for Magnetic Resonance in Medicine (ISMRM), 2005.
H.D. Rosas, P. Yu, Tuch, Hevelone, D.H. Salat, B. Fischl, Pathological alterations of the Corpus Callosum in Huntington's Disease: a combined DTI and Morphometric Study. Neuroimage Volume 26, Suppl 1, Page S21, Organization for Human Brain Mapping Annual Meeting, 2005.
D.H. Salat, P. Yu, D.S. Tuch, N.D. Hevelone, B. Fischl, H.D. Rosas, Detailed Analysis of Age-related Changes in he Corpus Calllosum: Combined DTI and Morphometric MRI. Neuroimage, Volume 26, Suppl 1, Page S47, Organization for Human Brain Mapping Annual Meeting, 2005.
Beg, R.L. Buckner, B. Fischl, Y. Park, Ceyhan, C.E. Priebe, Beritoglu, Kolasny, T. Brown, B. Quinn, P. Yu, et al., Patten classification of hippocampal shape analysis in a study of Alzheimer's Disease. Neuroimage, Volume 26, Suppl 1, Page S39, Organization for Human Brain Mapping Annual Meeting, 2005.

Teaching

Applied Nuclear Physics: Assisted in preparing course materials and grading homework; organized weekly recitations, reviews, and office hours.
Nuclear Engineering Laboratory: Instructed labs and graded lab reports.

In the media

Our research work in reported by:
    MIT Tech Talk Model helps researchers 'see' brain development
Chinese Xinhua news agency http://news.xinhuanet.com/world/2007-04/13/content_5972192.htm
    United Press International Scientists seek 'see' brain development
    HMS Focus HST Forum: Decoding Health and Disease
http://www.medicalnewstoday.com
http://www.medilexicon.com
http://www.hospitalsworldwide.com

Misc

MIT Tech Dumpling Making