The alignment file shows conservation of a human miRNA in many species:
  • human miRNA sequence and its secondary folding
  • section of the UCSC multi-way alignment that contains the human miRNA precursor
  • indication of the mature and seed (2-8nt) regions
  • known miRNAs in the alignment region, with miRbase links, and experimental evidence
  • links to genome assembly for each species


Coloring of nucleotides:




not overlapping
w/ known miRNA 		 
overlapping
w/ known miRNA
conserved
 ·
·
conserved in mature miRNA ·
·
conserved in miRNA seed •
•
unconserved in miRNA seed A C G T
A C G T
unconserved not in miRNA seed A C G T
A C G T