Peter G Mikhael

Chemical codes promote selective compartmentalization of proteins

Henry Kilgore^‡, Itamar Chinn ^‡, Peter G. Mikhael^‡, Ilan Mitnikov^‡, Catherine Van Dongen, Guy Zylberberg, Lena Afeyan, Salman Banani, Susana Wilson-Hawken, Tony Lee, Regina Barzilay, Richard Young

bioRxiv. 2024.

CLIPZyme: Reaction-Conditioned Virtual Screening of Enzymes

Peter G. Mikhael^‡, Itamar Chinn ^‡, Regina Barzilay

International Conference on Machine Learning. 2024.

Role of sex in lung cancer risk prediction based on single low-dose chest computed tomography

Judit Simon ^‡, Peter G. Mikhael^‡, Ismail Tahir, Alexander Graur, Stefan Ringer, Amanda Fata, Yang Chi-Fu Jeffrey, Jo-Anne Shepard, Francine Jacobson, Regina Barzilay, Lecia V. Sequist, Lydia E. Pace, Florian J. Fintelmann

Nature Scientific Reports. 2023.

Distinct chemical environments in biomolecular condensates

Henry R. Kilgore^‡, Peter G. Mikhael^‡, Kalon J. Overholt^‡, Ann Boija, Nancy M. Hannett, Catherine Van Dongen, Tong Ihn Lee, Young-Tae Chang, Regina Barzilay, Richard A. Young

Nature Chemical Biology. 2023.

Artificial Intelligence and Machine Learning in Lung Cancer Screening

Scott J. Adams, Peter G. Mikhael, Jeremy Wohlwend, Regina Barzila, yLecia V. Sequist, Florian J. Fintelmann

Thoracic Surgery Clinics. 2023.

Sybil: A validated deep learning model to predict future lung cancer risk from a single low-dose chest computed tomography

Peter G. Mikhael^‡, Jeremy Wohlwend^‡, Adam Yala, Ludvig Karstens, Justin Xiang, Angelo K. Takigami, Patrick P. Bourgouin, PuiYee Chan, Sofiane Mrah, Wael Amayri, Yu-Hsiang Juan, Cheng-Ta Yang, Yung-Liang Wan, Gigin Lin, Lecia V. Sequist, Florian J. Fintelmann, Regina Barzilay

Journal of Clinical Oncology. 2023.

Optimizing risk-based breast cancer screening policies with reinforcement learning

Adam Yala, Peter G. Mikhael, Constance Lehman, Gign Lin, Fredrik Strand, Yung-Liang Wang, Kevin Hughes, Siddharth Satuluru, Thomas Kim, Imon Banerjee, Judy Gichoya, Hari Trivedi, Regina Barzilay

Nature Medicine. 2022.

Multi-Institutional Validation of a Mammography-Based Breast Cancer Risk Model

Adam Yala, Peter G. Mikhael, Fredrik Strand, Gigin Lin, Siddharth Satuluru, Thomas Kim, Imon Banerjee, Judy Gichoya, Hari Trivedi, Constance D. Lehman, Kevin Hughes, David J. Sheedy, Lisa M. Matthis, Bipin Karunakaran, Karen E. Hegarty, Silvia Sabino, Thiago B. Silva, Maria C. Evangelista, Renato F. Caron, Bruno Souza, Edmundo C. Mauad, Tal Patalon, Sharon Handelman-Gotlib, Michal Guindy, Regina Barzilay

Journal of Clinical Oncology. 2021.

Toward robust mammography-based models for breast cancer risk

Adam Yala, Peter G. Mikhael, Fredrik Strand, Gigin Lin, Kevin Smith, Yung-Liang Wan, Leslie Lamb, Kevin Hughes, Constance Lehman, Regina Barzilay

Science Translational Medicine. 2021.

Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia patients with a lipoic acid analog

Michael A Reid, Shree Bose, Kristin M Pladna, Rebecca Anderson, Peter G. Mikhael, Zhengtao Xiao, Ziwei Dai, Shiyu Liu, Juan Liu, Timothy Pardee, Jason W. Locasale

medRxiv. 2021.

Nutrient availability shapes methionine metabolism in p16/MTAP-deleted cells

Sydney M. Sanderson, Peter G. Mikhael, Vijyendra Ramesh, Ziwei Dai, Jason W. Locasale

Science Advances. 2019.

Dietary methionine influences therapy in mouse cancer models and alters human metabolism

Xia Gao, Sydney M. Sanderson, Ziwei Dai, Michael A. Reid, Daniel E. Cooper, Min Lu, John P. Richie Jr, Amy Ciccarella, Ana Calcagnotto, Peter G. Mikhael, Samantha J. Mentch, Juan Liu, Gene Ables, David G. Kirsch, David S. Hsu, Sailendra N. Nichenametla, Jason W. Locasale

Nature. 2019.