Clare Poynton

cpoynton@csail.mit.edu

I am a PhD student in Medical Engineering and Medical Physics (MEMP) in the Harvard-MIT Division of Health Sciences and Technology (HST) and a member of the CSAIL medical vision group working under the supervision of William (Sandy) Wells.

Research Interests

I am interested in medical image reconstruction and analyis problems such as quantitative susceptibility mapping and phase-based analysis, segmentation, registration, and modeling and correction of artifacts in structural, functional, and diffusion MRI. My thesis research is focused on quantifying magnetic susceptibility and iron concentration in the brain from MR phase data. Non-invasive iron quantification is critical for advancing the study of neurodegenerative diseases such as Alzheimer's and Parkinson's where iron deposits are implicated in disease progression. Previously, I worked on atlas-based retrospective unwarping and registration of functional and diffusion MRI data for neurosurgical planning.

Publications

A variational approach to susceptibility estimation that is insensitive to B0 inhomogeneity.

Poynton C and Wells W.

Proceedings, International Society for Magnetic Resonance in Medicine (ISMRM), Montreal, Canada, 2011.
Atlas-based improved prediction of magnetic field inhomogeneity for distortion correction of EPI data.

Poynton C, Jenkinson M, Wells W.

Med Image Comput Comput Assist Interv (MICCAI), 12(2):951-9, 2009.
Fieldmap-Free Retrospective Registration and Distortion Correction for EPI-based Diffusion-Weighted Imaging.

Poynton C, Jenkinson M, Pierpaoli C, Wells W.

Proceedings, International Society for Magnetic Resonance in Medicine (ISMRM), Honolulu, HI, 2009.
Fieldmap-Free Retrospective Registration and Distortion Correction for EPI-based Functional Imaging.

Poynton C, Jenkinson M, Whalen S, Golby AJ, and Wells W.

Med Image Comput Comput Assist Interv (MICCAI), 11(2):271-279, 2008.
Delineating the Superior Temporal Gyrus using Dynamic Programming in Schizophrenia and Bipolar Disorder.

Pisano DV, Poynton C, Honeycutt NA, Barta PE, and Ratnanather JT.

International Congress on Schizophrenia Research, Colorado Springs, CO. 2007.
Statistical Analysis of Gender, Laterality and Diagnosis Effect on Planum Temporale.

Ceyhan E, Poynton C, Qiu A, Barta P, Miller MI, and Ratnanather JT.

Human Brain Mapping, Florence, 2006.
Probabilistic Tracking of Fiber Pathways Using Dynamic Programming.

Poynton C, Lal R, Ratnanather JT, Mori S, Boatman D, Miller MI.

Human Brain Mapping, Toronto, 2005.
A Cortical Analysis of the Laterality of the Planum Temporale in Hearing, Hearing-impaired and Central Auditory Processing Disorder Subjects.

Ratnanather JT, Poynton C, Ceyhan E, Osdoit A, Boatman D.

Midwinter Meeting of the Association for Research in Otolaryngology, New Orleans, 2005.
Visualizing Cortical Thickness on the Gray/White Cortical Surface.

Qiu A, Bitouk D, Ratnanather JT, Poynton C, Wang L, Boatman D, Barta P, Csernansky JG, Miller MI.

Human Brain Mapping, Toronto, 2005.
tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre.

Yoshino A, Setty SRG, Poynton C, Whiteman EL, Saint-Pol A, Burd CG, Johannes L, Holzbaur EL, Koval M, McCaffery JM and Marks MS.

J Cell Sci. 118: 2279-2293. 2005.