I just enabled SpamAssassin's Shortcircuit plugin on incoming.csail.mit.edu, which should really help with throughput in cases where ~900 messages suddenly show up from e.g. eventcalendar@csail.mit.edu.
I was recently asked for some statistics about how much mail we're seeing, what percent is identifiable as spam, etc. So here they are, the daily averages from week 40 of 2007:
* 181786 messages accepted per day
* 93656 messages rejected per day
* 46000 message examined by spamassassin per day
* 30017 messages tagged as spam by spamassassin per day
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