I am Director of Computational Biology at
where we aim to discover new therapies designed to act on the gut-body network for the treatment of
immuno inflammatory, metabolic, neurological diseases and cancer.
Prior to Evelo I was Head of Computational Biology & Data Science at
a gene control startup, and a Senior Scientist at
where I led an epigenomic natural history study and managed the Epigenetics and Cell & Gene Therapy group's NGS
analysis efforts for target discovery and the establishment of novel therapeutic modalities.
I trained as a Postdoctoral Fellow in the labs of
Harvard Stem Cell Institute
There I applied diverse NGS-based assays to study chromatin dynamics and the epigenetic regulation of pluripotent cells during differentiation -
identifying novel mechanisms and factors controlling cell state change and developing new methods for studying heterogeneous cell populations.
I completed my Ph.D. at
in the labs of Bonnie Berger and
Srini Devadas, and
Susan Lindquist at the
Whitehead Institute for Biomedical Research.
There I developed algorithms to characterize the folding and misfolding of proteins and RNA, and for modeling the inhibition of amyloid fibril formation.