For more technical details of the methods used by Segger:
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G. Pintilie, J. Zhang, W. Chiu, D. Gossard
"Identifying Components in 3D Density Maps of Protein Nanomachines by Multi-scale Segmentation"
In Life Science Systems and Applications Workshop, IEEE/NIH, pp. 44-47, 2009, IEEExplore, DSpace -
G. Pintilie
"Segmentation and Registration of Molecular Components in 3-Dimensional Density Maps from Cryo-Electron Microscopy"
Ph.D. Thesis., MIT, December 17, 2009 -
G. Pintilie, J. Zhang, T. Goddard, W. Chiu, D. Gossard
Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions
Journal of Structural Biology, vol. 170, Jun. 2010, pp. 427-438. Pubmed, ScienceDirect
Segger is maintained by Greg Pintilie and Tom Goddard. Please email comments and suggestions!